Health News
More than a million: understanding the UK's carers of people with cancer
According to this research there are over a million people who look after a loved-one with cancer that are potentially missing out on vital support and benefits. The report details the number and profile of the 1.1m people currently caring for someone with cancer in the UK and found that almost none (just 5%) have received a local authority Carersâ Assessment which enables them to access practical, emotional and financial support with their caring role.
Report
Macmillan Cancer Support - news (Source: The Kings Fund - Health Management Specialist Collection) Rewarding the Heroic Work of Midwives in Afghanistan - 20 January 2012
KABUL — In mid-December, Maliha walked for five days to reach Faizabad, the capital of Badakhshan, in northeastern Afghanistan, to receive her award as best midwife in the province. She felt proud as she went onstage to be honoured for her work in her community health clinic. (Source: UNFPA News) UDP-Glucuronosyltransferase Expression in Mouse Liver Is Increased in Obesity- and Fasting-Induced Steatosis [Articles]
UDP-glucuronosyltransferases (Ugt) catalyze phase II conjugation reactions with glucuronic acid, which enhances chemical polarity and the elimination from the body. Few studies have addressed whether Ugt expression and activity are affected by liver disease, such as steatosis. The purpose of this study was to determine whether steatosis induced by obesity or fasting could affect liver Ugt mRNA expression and activity. Male C57BL/6J and Lepob/ob (ob/ob) mice were fed ad libitum or food was withheld for 24 h. In steatotic livers of ob/ob mice, Ugt1a1, -1a6, -1a9, -2a3, -3a1, and -3a2 mRNA expression increased. Fasting, which also induced steatosis, increased hepatic Ugt1a1, -1a6, -1a7, -1a9, -2b1, -2b5, -2a3, -3a1, and -3a2 mRNA expression in mouse liver. Likewise, acetaminophen glucuronidation increased by 47% in hepatic microsomes from ob/ob mice compared with that in C57BL/6J mice, but not after fasting. In both steatosis models, Ugt induction was accompanied by increased aryl hydrocarbon receptor, constitutive androstane receptor (CAR), peroxisome proliferator-activated receptor (PPAR)-α, pregnane X receptor, nuclear factor (erythroid-derived 2)-like 2 (Nrf2), and peroxisome proliferator-activated receptor- coactivator-1α mRNA expression. In addition, fasting increased CAR, PPAR, and Nrf2 binding activity. The work points to hepatic triglyceride concentrations corresponding with nuclear receptor and Ugt expression. The findings indicate that steatosis significantly alters hepatic Ugt expression and activity, which could have a significant impact on determining circulating hormone levels, drug efficacy, and environmental chemical clearance.
Can Science Be Done Without Secrecy?
In his book, Reinventing Discovery: The New Era of Networked Science, Physicist Michael Nielsen discusses why scientists jealously guard their data and are slow to adopt online tools for collaboration. Nielsen talks about why attempts to create science wikipedias have failed.» E-Mail This » Add to Del.icio.us (Source: NPR Health and Science) sulindac, Clinoril
Title: sulindac, Clinoril
Category: Medications
Created: 12/31/1997
Last Editorial Review: 1/5/2012 amiodarone, Cordarone
Title: amiodarone, Cordarone
Category: Medications
Created: 12/31/1997
Last Editorial Review: 1/4/2012 Liberia: Firestone-Liberia Hosts Children's Surgery International
Heritage (Monrovia)-A medical team under the banner of Children's Surgery International (CSI) has arrived in Liberia to perform free surgical operations on afflicted Liberian children at the Firestone Medical Center in Duside, outside Harbel. According to a press release, the team, which touched down on Wednesday, January 25, 2012, at the Roberts International Airport (RIA) in Margibi County, was met upon arrival by an array of senior teammates of Firestone Liberia headed by Mr. Jorge Pezzimenti. (Source: AllAfrica News: Health and Medicine)
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